Make a global impact—join Repligen.
We’re united by a mission to inspire advances in bioprocessing as a preferred partner in the production of biologic drugs that improve human health worldwide. No matter your role or background, at Repligen, you will play a key part in shaping some of the most innovative and life-changing therapies in the world. We foster a culture of purpose, collaboration, and shared success—where every voice matters and every contribution drives progress. Join us!

Repligen is seeking a hands-on, skilled CNC Programmer and Operator with expertise in Mastercam to join our manufacturing team. This role is responsible for programming, setting up, and operating CNC milling machines to produce high-quality parts to specification. The ideal candidate will have a strong understanding of G-code, Mastercam, machining processes, and quality control standards.

• Create and modify CNC programs using Mastercam for milling operations.
• Set up and operate CNC milling machines (3-axis and/or 4/5-axis, depending on equipment).
• Select appropriate tools, speeds, and feeds for machining operations.
• Interpret engineering drawings, blueprints, and technical documents.
• Perform first-article and in-process inspections using precision measuring instruments (calipers, micrometers, indicators, etc.).
• Troubleshoot programming or machining issues to ensure quality and efficiency.
• Maintain accurate records of jobs, tooling, and setups.
• Ensure machines are properly maintained and cleaned.
• Follow all safety protocols and contribute to a safe and clean work environment.

Required Qualifications:

• Minimum 5 years of experience in CNC milling and programming.
• Proficient in Mastercam for creating and editing CNC programs.
• Proficient in using 3D model software to develop milling programs
• Strong knowledge of G-code.
• Experience reading and interpreting mechanical drawings and GD&T.
• Ability to work independently with minimal supervision.
• Strong attention to detail and commitment to quality.

Preferred Qualifications:

• Experience with multi-axis CNC milling machines.
• Familiarity with other CAD/CAM software (e.g., SolidWorks, Fusion 360).
• Experience in a high-mix, low-volume production environment.
• Lean manufacturing or continuous improvement experience.